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AtheNa Multi-Lyte®

One sample. One well. Multiple assays.

Published: 6/9/2026 | Modified: 7/13/2026
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About AtheNa Multi-Lyte®

Perform multiple assays with a single sample with the AtheNA Multi-Lyte® Instrument. The system is based on multiplex immunoassays, which are a cutting-edge technology combining the principles of fluorescence immunoassay (FIA)  with the advantages of microarrays to enable simultaneous detection and quantification of multiple target analytes in a single sample.

In the context of autoimmune and infectious diseases, this technology refers to the simultaneous detection and measurement of multiple analytes such as auto-antibodies and antigens.

This system uses polystyrene microspheres labelled internally with different ratios of two different fluorochrome (one red and one infrared) to provide a unique spectral signature. Each fluorochrome can have any of the 10 possible levels of fluorescence intensity, thereby reating a family of 100 spectrally addressed bead sets. The antigens corresponding to autoantibodies are bound to the microspheres. Each of the 100 microbeads that can be differentiated by their fluorescence carries a specific immobilized antigen for a single autoantibody. At the same time, a green laser excites the external reporter fluorescence to quantify the specific reaction related to each autoantibody.

Key Benefits

Discover the advantages of AtheNA Multi-Lyte® test system by Sebia.

  • Generate multiple reportable results simultaneously in the same well.

  • Flexible software with many reporting options – choose the results you want to see and report.

  • Proprietary Intra-Well Calibration Technology® runs calibrator beads in the same well, at the same time with your patient sample under the same conditions—why calibrate any other way?

  • Adds significant value by increasing the number of reportable wells per run.

  • Universal assay protocol minimizes training requirements.

  • SAVe Diluent® verification system ensures no well is missed.

  • 100 spectrally addressed bead sets

Featured tests for AtheNa Multi-Lyte®

Main Characteristics

Test menu

  • RF IgM Plus Test System
  • ANA-II Plus Test System
  • AIV Plus Test System
  • TPO/Tg Plus Test System
  • ToRCH IgG Plus Test System
  • EBV IgG Plus Test System
  • EBV-VCA Plus Test System
  • MMRV IgG Plus Test System
  • MMV IgG Plus Test System

Performance

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Instrument details

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Knowledge & Science

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This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country. Please contact your local Sebia representative. Information intended for healthcare professionals. Carefully read the instructions in the reagent package inserts and instrument manuals.