Serum Protein by Capillary Electrophoresis

High throughput Serum Protein Electrophoresis, with high resolution results.

Published date: 3/8/2021 | Modified date: 6/9/2026

About Serum Protein by Capillary Electrophoresis

Serum Protein Electrophoresis is a well-established technique routinely used in clinical laboratories to screen samples to detect protein abnormalities as monoclonal gammopathies (Multiple Myeloma, MGUS, Waldenström disease).

Key benefits

Serum Protein Electrophoresis (SPE) delivers high-quality results through full automation on capillary instruments, supporting clinicians at every stage of the myeloma patient journey.

Fully automated testing
for qualitative or quantitative analysis with fast serum protein separation and good resolution.
Direct visualisation of Serum Protein profile
for quick screening and identification of abnormal patterns.
Separation into major protein fractions
CAPI 3 PROTEIN(E) 6 kit enables the separation into six major fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, Gamma.
Ability to quantify abnormal peaks in two modes
Valley to valley or Baseline to top.

Main characteristics

Test principle

Serum Proteins are separated in silica capillaries by their electrophoretic mobility and the electroosmotic flow at high voltage in an alkaline buffer. Proteins are directly detected during migration by UV absorbance at 200 nm and quantified by the peak quantification tool.

Sample type

Serum

Performances

Full traceability and positive sample ID from primary tube samples
Full traceability and reagents management through RFID tags
Color-coded backlit reagent containers
Rapid validation via 96 profile mosaic display

Sensitivity

Monoclonal protein can be detected at a concentration as low as 19 mg/dL.
According to the mobility of the monoclonal component and polyclonal background, the sensitivity may vary.

Large autonomy

Samples up to 528 tubes (with tube loader)
> 2.5 hours protein testing

Throughput

Throughput (tests/hour)*

PROTEIN(E) 6

CAPILLARYS 3 OCTA 73
CAPILLARYS 3 TERA 99
CAPILLARYS 3 TERA MC3** 260
MINICAP FLEX-PIERCING 18

IMMUNOTYPING

CAPILLARYS 3 OCTA 9
CAPILLARYS 3 TERA 12
CAPILLARYS 3 TERA MC3** 34
MINICAP FLEX-PIERCING 2

*Firmware-dependent; contact your local Sebia representative for current information.
**Maximum Capacity or MC designation refers to Tube Loader CAPILLARYS 3 - P/N: 1249 and Rack Conveyor CAPILLARYS 3 - P/N: 1250 associated with CAPILLARYS 3 TERA - P/N: 1246.

Product details

CAPI 3 PROTEIN(E) 6 – P/N: 2503
MINICAP PROTEIN(E) 6 – P/N: 2203

Knowledge & Science

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