Distinctive shift technology
HYDRASHIFT daratumumab and HYDRASHIFT isatuximab avoid daratumumab or isatuximab interference on HYDRAGEL IF tests.
HYDRASHIFT
Avoid interferences due to therapeutic Monoclonal Antibody with HYDRASHIFT Portfolio.
About HYDRASHIFT
Therapeutic monoclonal antibody (mAb) inclusion in Multiple Myeloma treatment regimens offer patients significant improvements in clinical outcomes. daratumumab and isatuximab are human mAb targeting CD38 used in Multiple Myeloma treatment regimens.
HYDRASHIFT avoids therapeutic mAb interference on Immunofixation interpretation assays.
Key benefits
HYDRASHIFT : A simple and reliable solution to eliminate interferences from therapeutic monoclonal antibodies.
Trust in the results
HYDRASHIFT reduce the risk of incorrect IF interpretation to improve therapy monitoring.
Easy to implement
Fully integrated into IF protocol without sample pre-treatment for a standardized process compliant to IMWG guidelines.
Follow IMWG guidelines
Process compliant to IMWG guidelines to assess response to treatment in patient with Multiple Myeloma.
Main characteristics
Test principle
HYDRASHIFT is an immunofixation procedure performed on HYDRAGEL IF 2/4 gel and based on the creation of a mAb/ anti mAb immune complex shift mAb drug (daratumumab or isatuximab) in alpha zone.
This complex is visible in the IgG and kappa immunofixation tracks. A negative HYDRASHIFT result demonstrates the absence of endogenous M-protein.
Sample type
Serum
Performances
Sensitivity
The limit of immune complex visualized is 0.3 g/L.
Product details
- HYDRASHIFT 2/4 daratumumab (20 tests) – P/N: 4639
- daratumumab control – P/N: 4765
- HYDRASHIFT 2/4 isatuximab (40 tests) – P/N: 4642
- isatuximab control P/N: 4764
Knowledge & Science
No content available.
HYDRASHIFT test can be performed on the following instruments
Large menu with high quality results on gel electrophoresis.
Tests related to HYDRASHIFT
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